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O14 In vitro models for oral malodor

Identifieur interne : 007452 ( Main/Exploration ); précédent : 007451; suivant : 007453

O14 In vitro models for oral malodor

Auteurs : J. Greenman [Royaume-Uni] ; P. Spencer [Royaume-Uni] ; C. Mckenzie [Royaume-Uni] ; S. Saad [Royaume-Uni]

Source :

RBID : ISTEX:7E9E5CEAC667960084D45504F7EB2655B95C55C5

Descripteurs français

English descriptors

Abstract

We start with a description of what we mean by a model and introduce the idea of using different types of model to answer different types of questions. A model is a representation of some real phenomena and contains aspects or elements of the real system to be modelled. The model reflects (or duplicates) the type of behaviour (or mechanisms) seen in the real system. The main characteristic of any model is the mapping of elements or parameters found in the system being studied (e.g. tongue dorsum biofilm in situ) on to the model being devised (e.g. laboratory perfusion biofilm). Such parameters include correct physico‐chemical (abiotic) conditions as well as biotic conditions that occur in both model and reality. The main purpose of a model is to provide information that better explains the processes observed or thought to occur in the real system. Such models can be abstract (mental, conceptual, theoretical, mathematical or computational) or ‘physical’ e.g. in the form of a real disaggregated in vitro system or laboratory model. A wide range of different model systems have been used in oral biofilm research. These will be briefly reviewed with special emphasis on those models that have contributed most to knowledge in breath odour research. The different model systems used in breath odour research will be compared with each other regarding their advantages, disadvantages and main applications. Finally, the requirements for developing an overall ‘bad breath model’ from considering the processes as a whole (real oral cavity; substrates in saliva;, biotransformation; odour gases in the breath) and extending this to the detection of malodour by the human nose (and all stages in between) will be outlined and discussed.

Url:
DOI: 10.1111/j.1601-0825.2005.01105_14.x


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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<term>Absolute value</term>
<term>Amine</term>
<term>Anaerobe</term>
<term>Anaerobic</term>
<term>Average level</term>
<term>Aviv</term>
<term>Aviv university</term>
<term>Avour</term>
<term>Avours</term>
<term>Baseline</term>
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<term>Breath freshening dentifrice</term>
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<term>Control groups</term>
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<term>Dentulous subjects</term>
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<term>Denture brush</term>
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<term>Elderly patients</term>
<term>Elderly people</term>
<term>Elderly population</term>
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<term>Essential oils</term>
<term>Examiner variation</term>
<term>Ezaki glico</term>
<term>Freshening</term>
<term>Gabriela goldschleger school</term>
<term>General health</term>
<term>Gingival</term>
<term>Gingival index</term>
<term>Gingivalis</term>
<term>Graduate school</term>
<term>Guideline</term>
<term>Halimeter</term>
<term>Halitometry</term>
<term>Halitosis</term>
<term>Halitosis samples</term>
<term>Halitosis therapy</term>
<term>Halitosis unit</term>
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<term>Hedonic</term>
<term>High intensity</term>
<term>Human nose</term>
<term>Hygiene</term>
<term>Intraoral oxygen release device</term>
<term>Japan objective</term>
<term>Laser</term>
<term>Laser treatment</term>
<term>Lethal photosensitization</term>
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<term>Methyl mercaptan</term>
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<term>Microbiota</term>
<term>Microorganism</term>
<term>Molecular weight amines</term>
<term>Morning breath</term>
<term>Mouthrinse</term>
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<term>Odor judge scores</term>
<term>Odor judges</term>
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<term>Odour judges</term>
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<term>Oral care</term>
<term>Oral care products</term>
<term>Oral cavity</term>
<term>Oral diseases</term>
<term>Oral diseases abstracts</term>
<term>Oral examination</term>
<term>Oral halitosis</term>
<term>Oral health</term>
<term>Oral health care</term>
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<term>Oral malodor research</term>
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<term>Organoleptic measurements</term>
<term>Organoleptic scale</term>
<term>Organoleptic score</term>
<term>Organoleptic scores</term>
<term>Organoleptic test</term>
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<term>Placebo</term>
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<term>Polyester bags</term>
<term>Porphyromonas gingivalis</term>
<term>Present study</term>
<term>Preventive dentistry</term>
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<term>Saliva samples</term>
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<term>Sampling bags</term>
<term>Sensor array</term>
<term>Sensor responses</term>
<term>Social function</term>
<term>Square test</term>
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<term>Study population</term>
<term>Subjective symptoms</term>
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<term>Sulfur compounds</term>
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<term>Tongue microbiota</term>
<term>Toothpaste</term>
<term>Triclosan</term>
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<term>Uoride dentifrice</term>
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<term>Absolute value</term>
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<term>Average level</term>
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<term>Aviv university</term>
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<term>Avours</term>
<term>Baseline</term>
<term>Behavioral factors</term>
<term>Breath freshening</term>
<term>Breath freshening dentifrice</term>
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<term>Breath odor</term>
<term>Catholic university leuven</term>
<term>Ch3sh</term>
<term>Ch3sh concentration ratio</term>
<term>Clinical attachment level</term>
<term>Clinical study</term>
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<term>Control group</term>
<term>Control groups</term>
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<term>Essential oils</term>
<term>Examiner variation</term>
<term>Ezaki glico</term>
<term>Freshening</term>
<term>Gabriela goldschleger school</term>
<term>General health</term>
<term>Gingival</term>
<term>Gingival index</term>
<term>Gingivalis</term>
<term>Graduate school</term>
<term>Guideline</term>
<term>Halimeter</term>
<term>Halitometry</term>
<term>Halitosis</term>
<term>Halitosis samples</term>
<term>Halitosis therapy</term>
<term>Halitosis unit</term>
<term>Headspace</term>
<term>Health status</term>
<term>Hedonic</term>
<term>High intensity</term>
<term>Human nose</term>
<term>Hygiene</term>
<term>Intraoral oxygen release device</term>
<term>Japan objective</term>
<term>Laser</term>
<term>Laser treatment</term>
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<term>Light energy</term>
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<term>Microbiota</term>
<term>Microorganism</term>
<term>Molecular weight amines</term>
<term>Morning breath</term>
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<term>Odor judge scores</term>
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<term>Odour judges</term>
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<term>Oral care</term>
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<term>Oral diseases</term>
<term>Oral diseases abstracts</term>
<term>Oral examination</term>
<term>Oral halitosis</term>
<term>Oral health</term>
<term>Oral health care</term>
<term>Oral hygiene</term>
<term>Oral malodor</term>
<term>Oral malodor intensity</term>
<term>Oral malodor research</term>
<term>Oral malodour</term>
<term>Oral microbiota</term>
<term>Organoleptic</term>
<term>Organoleptic assessment</term>
<term>Organoleptic measurement</term>
<term>Organoleptic measurements</term>
<term>Organoleptic scale</term>
<term>Organoleptic score</term>
<term>Organoleptic scores</term>
<term>Organoleptic test</term>
<term>Other body odors</term>
<term>Other hand</term>
<term>Oxidative</term>
<term>Oxidative damage</term>
<term>Periodontal</term>
<term>Periodontal disease</term>
<term>Periodontal therapy</term>
<term>Periodontitis</term>
<term>Periodontology</term>
<term>Periodontopathic bacteria</term>
<term>Placebo</term>
<term>Plaque</term>
<term>Plaque index</term>
<term>Polyester bags</term>
<term>Porphyromonas gingivalis</term>
<term>Present study</term>
<term>Preventive dentistry</term>
<term>Quest breath freshness panel</term>
<term>Randomized</term>
<term>Real system</term>
<term>Relative amount</term>
<term>Research center</term>
<term>Saliva</term>
<term>Saliva samples</term>
<term>Salivarius</term>
<term>Sampling bags</term>
<term>Sensor array</term>
<term>Sensor responses</term>
<term>Social function</term>
<term>Square test</term>
<term>Statistical analysis</term>
<term>Study population</term>
<term>Subjective symptoms</term>
<term>Sulfur</term>
<term>Sulfur compounds</term>
<term>Sulphide</term>
<term>Time point</term>
<term>Tongue brush</term>
<term>Tongue cleaning</term>
<term>Tongue coat</term>
<term>Tongue coating</term>
<term>Tongue coating score</term>
<term>Tongue coating status</term>
<term>Tongue dorsum</term>
<term>Tongue microbiota</term>
<term>Toothpaste</term>
<term>Triclosan</term>
<term>Trimethylamine</term>
<term>University school</term>
<term>Unpleasant breath</term>
<term>Uoride</term>
<term>Uoride dentifrice</term>
<term>Vocs</term>
<term>Volatile</term>
<term>Volatile sulfur compounds</term>
<term>Volatile sulphur compounds</term>
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<term>Wide range</term>
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<front>
<div type="abstract" xml:lang="en">We start with a description of what we mean by a model and introduce the idea of using different types of model to answer different types of questions. A model is a representation of some real phenomena and contains aspects or elements of the real system to be modelled. The model reflects (or duplicates) the type of behaviour (or mechanisms) seen in the real system. The main characteristic of any model is the mapping of elements or parameters found in the system being studied (e.g. tongue dorsum biofilm in situ) on to the model being devised (e.g. laboratory perfusion biofilm). Such parameters include correct physico‐chemical (abiotic) conditions as well as biotic conditions that occur in both model and reality. The main purpose of a model is to provide information that better explains the processes observed or thought to occur in the real system. Such models can be abstract (mental, conceptual, theoretical, mathematical or computational) or ‘physical’ e.g. in the form of a real disaggregated in vitro system or laboratory model. A wide range of different model systems have been used in oral biofilm research. These will be briefly reviewed with special emphasis on those models that have contributed most to knowledge in breath odour research. The different model systems used in breath odour research will be compared with each other regarding their advantages, disadvantages and main applications. Finally, the requirements for developing an overall ‘bad breath model’ from considering the processes as a whole (real oral cavity; substrates in saliva;, biotransformation; odour gases in the breath) and extending this to the detection of malodour by the human nose (and all stages in between) will be outlined and discussed.</div>
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